Cleaning solvent methylene chloride is one of the organic solvents commonly used in organic laboratories. As one of the few polar aprotic non-nucleophilic solvents, it has a very good solubility for many organic substances, whether it is insoluble in petroleum ether. , or a small molecule that is insoluble in dimethyl sulfoxide, and dissolves quite well in dichloromethane.

Cleaning solvent methylene chloride can sometimes greatly reduce the sample volume when using wet loading in packed column chromatography (although it is sometimes necessary to increase the column length to prevent tailing). In terms of extraction, it is practically insoluble in water, denser, distinctly layered, and rarely emulsified. Its boiling point is very low and it evaporates easily.

Although Cleaning solvent methylene chloride has a pungent odor similar to ether, it is insoluble in water, soluble in ethanol and ether, and is a good organic solvent, but it is toxic, so certain measures need to be taken during transportation and use to ensure Safety.